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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | ERA | YEAR | Open Postseason Leaderboard |
|---|---|---|---|---|
| 1 | Alejandro Cruz | 0.494 | 2051-2052 | |
| 2 | José Zúñiga# | 0.545 | 2061-2061 | |
| 3 | Félix Jiménez | 0.831 | 2038-2040 | |
| 4 | Yi-lin An | 1.038 | 2024-2030 | |
| 5 | Manuel Ruíz | 1.059 | 2037-2048 | |
| 6 | Nick Rivers# | 1.218 | 2050-2053 | |
| 7 | Bill Keefe# | 1.239 | 2045-2046 | |
| 8 | Jarred Perkins | 1.452 | 2037-2038 | |
| 9 | Manny Cruz# | 1.604 | 2057-2059 | |
| 10 | Bob Coleman | 1.766 | 2030-2030 | |
| 11 | Rubén Pereira | 1.815 | 2025-2029 | |
| 12 | David Carpenter | 1.969 | 2045-2045 | |
| 13 | José Hernández# | 2.000 | 2047-2047 | |
| 14 | Owen Mcintyre | 2.077 | 2054-2054 | |
| 14 | Juan Sánchez | 2.077 | 2027-2028 | |
| 16 | Raza Zardari# | 2.160 | 2059-2061 | |
| 17 | Jorge Costa | 2.432 | 2045-2049 | |
| 18 | Héctor Delgado# | 2.480 | 2055-2059 | |
| 18 | Lloyd Mallandain# | 2.480 | 2054-2056 | |
| 20 | Tim Pierce | 2.531 | 2033-2035 | |
| 21 | Takeo Aoki | 2.558 | 2033-2035 | |
| 22 | Kwan-cheol Yi | 2.571 | 2045-2054 | |
| 23 | Juan Cruz# | 2.613 | 2045-2047 | |
| 23 | Alfonso Rodríguez | 2.613 | 2056-2057 | |
| 23 | Aras Yilmanz | 2.613 | 2045-2050 | |
| 26 | Takafumi Ikeda | 2.662 | 2048-2050 | |
| 27 | António Coztes | 2.700 | 2045-2047 | |
| 28 | Pat Rhodes# | 2.784 | 2056-2056 | |
| 29 | Quintin Birss | 2.888 | 2041-2054 | |
| 30 | Gene Cousineau# | 2.925 | 2060-2061 | |
| 31 | Armando Jiménez | 2.935 | 2019-2024 | |
| 32 | Bartolo Chiaudani | 2.967 | 2028-2045 | |
| 33 | Monte Evans | 3.062 | 2050-2054 | |
| 34 | Jeffrey Flowers | 3.184 | 2049-2053 | |
| 35 | Roger Guth | 3.185 | 2026-2029 | |
| 36 | Dewey McKim# | 3.228 | 2053-2055 | |
| 37 | Jackson Wear | 3.240 | 2048-2051 | |
| 38 | Naruhiko Watanabe | 3.375 | 2045-2046 | |
| 39 | Gilberto Morales | 3.432 | 2023-2028 | |
| 40 | Niko Andric# | 3.475 | 2053-2056 | |
| 41 | Raúl Hernández# | 3.560 | 2059-2061 | |
| 41 | Lucas Meech | 3.560 | 2027-2030 | |
| 43 | Javier Aranda | 3.611 | 2026-2027 | |
| 44 | Mike James | 3.630 | 2050-2052 | |
| 45 | Will Hernández# | 3.695 | 2059-2061 | |
| 46 | Jorge García# | 3.734 | 2052-2056 | |
| 47 | José Rosas | 3.857 | 2024-2026 | |
| 48 | Micah Annlar | 3.923 | 2047-2050 | |
| 49 | Rick Goulding | 4.091 | 2045-2052 | |
| 50 | Mei-shan Ngui | 4.235 | 2029-2030 | |
| 51 | Mohsin Janjua | 4.320 | 2055-2057 | |
| 51 | Firas Ahmed# | 4.320 | 2060-2061 | |
| 53 | Jack Collin | 4.339 | 2029-2030 | |
| 54 | Matt Mills | 4.418 | 2025-2038 | |
| 55 | Jorge Casillas# | 4.454 | 2057-2057 | |
| 56 | Fernando Márquez | 4.531 | 2029-2030 | |
| 57 | John Eilers | 4.832 | 2055-2056 | |
| 58 | Juan Tobías# | 4.947 | 2058-2061 | |
| 59 | Charlie Worley# | 4.969 | 2059-2061 | |
| 60 | Ijo Djajadiningrat# | 5.174 | 2059-2061 | |
| 61 | Miguel Flores | 5.545 | 2027-2028 | |
| 62 | Omer bin Wasim# | 5.934 | 2059-2061 | |
| 63 | Mu'tazz bin Akram# | 6.480 | 2045-2047 | |
| 64 | Pepe Elizarraraz | 6.568 | 2026-2030 | |
| 65 | Xavier Silva | 7.181 | 2025-2028 | |
| 66 | Jed Parra | 7.579 | 2027-2031 |
