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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | ERA | YEAR | Open Career Leaderboard |
|---|---|---|---|---|
| 1 | Raza Zardari# | 0.836 | 2059 | |
| 2 | Edgardo Morán | 0.865 | 1999 | |
| 3 | Rick Wells | 0.879 | 2001 | |
| 4 | Sandy Mallandaine# | 0.922 | 2057 | |
| 5 | Gernot Frece | 0.952 | 2051 | |
| 6 | Leonard Puckett | 0.954 | 2006 | |
| 7 | Anthony Brown | 0.955 | 2007 | |
| 8 | Pete Hulett# | 0.960 | 2055 | |
| 9 | Johnny Carr# | 0.964 | 2057 | |
| 10 | Júlio Gonzáles | 1.023 | 2040 | |
| 11 | Rafael Cuestas | 1.032 | 2006 | |
| 12 | Archie Cartwright | 1.035 | 2005 | |
| 12 | Archie Cartwright | 1.035 | 2004 | |
| 14 | Alejandro Cruz | 1.083 | 2052 | |
| 15 | Dave Whittier | 1.085 | 2036 | |
| 16 | Phil Rose | 1.102 | 2023 | |
| 17 | Loan Duval# | 1.110 | 2054 | |
| 18 | Virgile Ardizzone | 1.136 | 2039 | |
| 19 | Carlos Zalvidea | 1.139 | 2004 | |
| 20 | Juan Romero# | 1.157 | 2060 | |
| 21 | Zhuo-cheng Hsia | 1.160 | 2039 | |
| 22 | Juan Silva# | 1.168 | 2059 | |
| 23 | Lawrence Forest# | 1.184 | 2058 | |
| 24 | Álex León# | 1.190 | 2054 | |
| 25 | Leonard Puckett | 1.191 | 2004 | |
| 26 | Bobby McHone# | 1.198 | 2059 | |
| 27 | Nick Rivers# | 1.202 | 2053 | |
| 28 | Raúl Vásquez | 1.219 | 2041 | |
| 29 | Tarik Walliyullah# | 1.227 | 2059 | |
| 30 | Juan García | 1.243 | 1997 | |
| 31 | Tomás Valdéz | 1.248 | 2006 | |
| 32 | Bob Blaisdell | 1.266 | 2000 | |
| 32 | Sam Druff# | 1.266 | 2051 | |
| 34 | Woody Adams | 1.274 | 2007 | |
| 35 | Tom Sharp | 1.286 | 1998 | |
| 35 | Nelson Middlebrooks# | 1.286 | 2059 | |
| 37 | Francisco Moreno# | 1.291 | 2059 | |
| 38 | David Mazariegos | 1.292 | 2011 | |
| 38 | Jesús Martínez | 1.292 | 2044 | |
| 40 | Brian Meister | 1.303 | 1998 | |
| 41 | Jaigupta Bhanghoo# | 1.317 | 2061 | |
| 42 | Brent Lindsey | 1.320 | 2001 | |
| 43 | José Bermúdez | 1.322 | 2023 | |
| 44 | Manny Cruz# | 1.333 | 2059 | |
| 45 | Mark Livingston | 1.355 | 2008 | |
| 46 | Lawrence Hutchison | 1.359 | 2010 | |
| 47 | Kreshnik Bizi# | 1.361 | 2057 | |
| 48 | Paul Hales | 1.375 | 1998 | |
| 48 | Alfonso Cruz | 1.375 | 2039 | |
| 48 | Mike Bragg | 1.375 | 2035 | |
| 51 | António Santos | 1.382 | 2008 | |
| 52 | Jim Hill | 1.385 | 2006 | |
| 53 | Matt Keller | 1.387 | 2016 | |
| 54 | Augusto Román | 1.390 | 2027 | |
| 55 | Lenya Nikushkin# | 1.394 | 2058 | |
| 55 | Rashid Syed# | 1.394 | 2059 | |
| 57 | Alfredo Sánchez | 1.414 | 2038 | |
| 57 | Martin Villa | 1.414 | 2052 | |
| 59 | António Ayala | 1.415 | 2017 | |
| 60 | Miklas Wils | 1.421 | 2036 | |
| 61 | Héctor Delgado# | 1.432 | 2055 | |
| 62 | Donald Harris | 1.439 | 2001 | |
| 63 | Joseph James# | 1.449 | 2059 | |
| 64 | Ricardo Soriano | 1.462 | 2010 | |
| 65 | Alejandro Cruz | 1.466 | 2051 | |
| 66 | Júlio Madrigal | 1.473 | 2035 | |
| 67 | Alberto Leal | 1.481 | 2035 | |
| 68 | Ciro Caredda | 1.492 | 2002 | |
| 69 | José Leyva | 1.495 | 2009 | |
| 70 | Juan Pérez | 1.500 | 2040 | |
| 71 | Takashi Yamamoto# | 1.519 | 2057 | |
| 72 | Guillermo Sánchez | 1.521 | 2038 | |
| 73 | Oliver Villegas | 1.528 | 2037 | |
| 74 | Jerry Anaya# | 1.537 | 2059 | |
| 75 | Tom Sullivan# | 1.540 | 2061 | |
| 76 | Keizo Kaneko | 1.543 | 2040 | |
| 77 | Vincente Medrano | 1.546 | 2035 | |
| 78 | António Rodríguez | 1.548 | 2039 | |
| 79 | Glenn Hargrove# | 1.552 | 2053 | |
| 80 | Wally Leonard | 1.553 | 2013 | |
| 81 | Endres Kümblin | 1.556 | 2055 | |
| 82 | Calvin Meyer | 1.571 | 2002 | |
| 83 | Quintin Birss | 1.574 | 2052 | |
| 84 | Johnny Ginn | 1.580 | 1998 | |
| 85 | Brian Whitford# | 1.584 | 2056 | |
| 86 | Alan Hucknall | 1.588 | 2004 | |
| 86 | Carthage Knowlton# | 1.588 | 2061 | |
| 86 | Jim Davis | 1.588 | 2011 | |
| 86 | Jeremy Crawford | 1.588 | 2048 | |
| 90 | Cipriano Morales | 1.595 | 2054 | |
| 91 | Vincente Venalde | 1.599 | 2039 | |
| 91 | Bruce Lund | 1.599 | 1998 | |
| 93 | Vicente Méndez | 1.601 | 2038 | |
| 94 | Pedro Costello | 1.602 | 2039 | |
| 94 | Cliff Sweeny | 1.602 | 2000 | |
| 96 | Clayton O'Donnell | 1.608 | 2010 | |
| 97 | Calvin Meyer | 1.609 | 2008 | |
| 98 | Michael Myrie | 1.613 | 1998 | |
| 99 | Carlos Ramírez | 1.614 | 2022 | |
| 100 | Vincente Hernández# | 1.615 | 2058 |
