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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | ERA | YEAR | Open Career Leaderboard |
|---|---|---|---|---|
| 1 | Ken Crawford | 0.432 | 2023 | |
| 2 | Juan Jose Eilzando | 0.506 | 2026 | |
| 3 | Anthony Soprano | 0.643 | 2018 | |
| 4 | Mario González | 0.707 | 2020 | |
| 5 | Reggie Gascoigne | 0.720 | 2030 | |
| 6 | Fernando Castro | 0.735 | 2021 | |
| 6 | César De La Cruz | 0.735 | 2025 | |
| 8 | Luis Valenzuela | 0.789 | 2022 | |
| 9 | Al Compton | 0.894 | 2018 | |
| 10 | Ignacio Rodríguez | 0.912 | 2021 | |
| 11 | Gary Peters | 0.936 | 2028 | |
| 12 | Van Willard | 0.944 | 2026 | |
| 13 | José Lozano | 0.959 | 2024 | |
| 14 | Reynaldo Limón | 0.993 | 2023 | |
| 15 | Albert Ramírez | 1.000 | 2038 | |
| 16 | Tony Nelson | 1.063 | 2027 | |
| 17 | Mike Bailey | 1.080 | 2024 | |
| 18 | Alberto Vargas | 1.107 | 2024 | |
| 19 | Julián Domínguez | 1.125 | 2027 | |
| 20 | Domingo González | 1.149 | 2018 | |
| 21 | Nuhmete Nuri | 1.154 | 2052 | |
| 22 | José Lozano | 1.174 | 2026 | |
| 23 | Gustavo Fring | 1.187 | 2028 | |
| 24 | Juan Jose Eilzando | 1.209 | 2024 | |
| 25 | Edgardo Rodríguez | 1.227 | 2028 | |
| 26 | Elwood Blues | 1.243 | 2027 | |
| 27 | Víctor Elizondo | 1.246 | 2028 | |
| 28 | Ken Bautista# | 1.263 | 2054 | |
| 29 | Brooks McHall | 1.278 | 2017 | |
| 30 | José Sánchez | 1.279 | 2020 | |
| 31 | António Ayala | 1.280 | 2018 | |
| 32 | Chris Park | 1.322 | 2028 | |
| 33 | Alberto López | 1.333 | 2019 | |
| 34 | Esteban Gil | 1.340 | 2026 | |
| 35 | Leonor Betote | 1.342 | 2017 | |
| 36 | José García | 1.370 | 2024 | |
| 37 | Alberto Peña | 1.380 | 2024 | |
| 38 | Alberto López | 1.390 | 2017 | |
| 38 | Abel Gibson | 1.390 | 2029 | |
| 40 | Rob Snyder | 1.401 | 2028 | |
| 41 | Edgardo Rodríguez | 1.410 | 2025 | |
| 42 | Mark Andrade | 1.443 | 2027 | |
| 43 | Rafail Coman# | 1.444 | 2059 | |
| 44 | Gary Estes* | 1.459 | 2016 | |
| 45 | Sinclair Kooijman | 1.464 | 2016 | |
| 46 | Ramón Vidrio | 1.477 | 2021 | |
| 47 | Ash Davenport | 1.481 | 2053 | |
| 48 | Carey Ling | 1.487 | 2047 | |
| 49 | Carlos Cruz | 1.488 | 2028 | |
| 50 | Enrique Herrera | 1.490 | 2020 | |
| 51 | Domingo Navarro | 1.500 | 2022 | |
| 51 | Luis Galván | 1.500 | 2028 | |
| 53 | Francisco Moreno# | 1.510 | 2060 | |
| 54 | Joe McCord | 1.512 | 2019 | |
| 55 | Chandler Hall | 1.518 | 2038 | |
| 56 | Chiang-hui Lou | 1.520 | 2035 | |
| 57 | Javier Reyes | 1.524 | 2051 | |
| 58 | Ángelo Ríos | 1.528 | 2025 | |
| 58 | Bobby Guthrington | 1.528 | 2016 | |
| 60 | Gerardo Castillo | 1.532 | 2023 | |
| 60 | Anastasio Vázquez | 1.532 | 2021 | |
| 62 | Abe Colbert, Jr. | 1.537 | 2026 | |
| 63 | Álex León# | 1.541 | 2052 | |
| 64 | José Reyes | 1.554 | 2028 | |
| 64 | Alfredo Martínez | 1.554 | 2027 | |
| 66 | José Castillo | 1.562 | 2020 | |
| 67 | Kevin Beasley | 1.568 | 2052 | |
| 68 | Yoshinori Sugiyama | 1.574 | 2053 | |
| 69 | Skip Stewart | 1.575 | 2017 | |
| 70 | Francisco Flores | 1.588 | 2028 | |
| 70 | Sancho Delgado | 1.588 | 2017 | |
| 70 | Manny Torres | 1.588 | 2022 | |
| 73 | Tony Canales | 1.599 | 2023 | |
| 74 | Esteban Navarro | 1.609 | 2017 | |
| 74 | Juan Martínez | 1.609 | 2022 | |
| 76 | Iván Flores# | 1.615 | 2055 | |
| 77 | Orlando Rúbio# | 1.620 | 2059 | |
| 78 | Robert Anderson | 1.624 | 2025 | |
| 79 | Naruhiko Kawano# | 1.625 | 2053 | |
| 80 | Chris Rader# | 1.630 | 2059 | |
| 81 | Esteban Ortíz | 1.631 | 2016 | |
| 82 | Kalaila Cobar# | 1.636 | 2060 | |
| 83 | Samir Qasim# | 1.656 | 2055 | |
| 84 | Alfredo Ortega | 1.662 | 2019 | |
| 85 | Ken Vázquez | 1.671 | 2028 | |
| 86 | Javier Castellanos | 1.676 | 2027 | |
| 87 | Chris Godwin | 1.678 | 2016 | |
| 88 | Orlando Bragaghio | 1.688 | 2023 | |
| 89 | Enrico Franco | 1.699 | 2023 | |
| 90 | Ken Vázquez | 1.709 | 2027 | |
| 91 | Pedro Díaz | 1.712 | 2040 | |
| 92 | Edgardo Ramírez# | 1.716 | 2057 | |
| 93 | Alfredo Elizarraraz | 1.720 | 2016 | |
| 94 | Ken Davis | 1.723 | 2019 | |
| 95 | Jimmy Greenwood | 1.727 | 2027 | |
| 96 | Allen Sullivan | 1.733 | 2052 | |
| 97 | Tarik Walliyullah# | 1.735 | 2060 | |
| 98 | António Salazar | 1.742 | 2017 | |
| 98 | Al Compton | 1.742 | 2019 | |
| 100 | Joost Breakwell | 1.748 | 2017 |
